American Airlines flight AA 5281: Multiple routes

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FLIGHT SCHEDULE
Direct Flights:
Daily 06:00 Chattanooga (CHA) 07:46 Dallas Fort Worth (DFW)
AA 5281 Non-stop Canadair CRJ 900 (CR9) 2:46 Effective 2026-01-06 through 2026-02-11
Daily 08:39 Cincinnati (CVG) 10:25 Charlotte (CLT)
AA 5281 Non-stop Canadair CRJ 900 (CR9) 1:46 Effective 2026-09-09 through 2026-10-04
Daily 08:41 Cincinnati (CVG) 10:25 Charlotte (CLT)
AA 5281 Non-stop Canadair CRJ 900 (CR9) 1:44 Effective 2026-05-21 through 2026-07-01
Daily 08:42 Cincinnati (CVG) 10:25 Charlotte (CLT)
AA 5281 Non-stop Canadair CRJ 900 (CR9) 1:43 Effective 2026-07-02 through 2026-08-04
Daily 08:44 Cincinnati (CVG) 10:25 Charlotte (CLT)
AA 5281 Non-stop Canadair CRJ 900 (CR9) 1:41 Effective 2026-08-05 through 2026-09-08
Daily 08:45 Cincinnati (CVG) 10:25 Charlotte (CLT)
AA 5281 Non-stop Canadair CRJ 900 (CR9) 1:40 Effective 2026-04-07 through 2026-05-20
Mon-Fri,Sun 10:20 Ronald Reagan Washington (DCA) 2 12:01 Rochester (ROC)
AA 5281 Non-stop Canadair CRJ 900 (CR9) 1:41 Effective 2026-02-12 through 2026-03-06
Mon-Fri,Sun 12:31 Rochester (ROC) 13:59 Ronald Reagan Washington (DCA) 2
AA 5281 Non-stop Canadair CRJ 900 (CR9) 1:28 Effective 2026-02-12 through 2026-03-06
Mon,Wed-Sun 20:45 Dallas Fort Worth (DFW) 22:53 Moline (MLI)
AA 5281 Non-stop Canadair CRJ 900 (CR9) 2:08 Effective 2026-03-08 through 2026-04-06
Tue 21:05 Dallas Fort Worth (DFW) 23:13 Moline (MLI)
AA 5281 Non-stop Canadair CRJ 900 (CR9) 2:08 Effective 2026-03-10 through 2026-03-31
Mon,Tue,Thu-Sun 23:00 Charlotte (CLT) 23:58 Greenville/Spartanburg (GSP)
AA 5281 Non-stop Canadair CRJ 900 (CR9) 0:58 Valid until 2026-01-05
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This flight number is listed as serving the following routes:


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American Airlines flight AA 5281: Multiple routes
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Select flight date:
FLIGHT SCHEDULE
Direct Flights:
American Airlines AA5281
06:00
Chattanooga (CHA)

07:46
Dallas Fort Worth (DFW)
Effective 2026-01-06 through 2026-02-11
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:46, non-stop
Canadair CRJ 900 (CR9)
Direct Flights:
American Airlines AA5281
08:39
Cincinnati (CVG)

10:25
Charlotte (CLT)
Effective 2026-09-09 through 2026-10-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:46, non-stop
Canadair CRJ 900 (CR9)
Direct Flights:
American Airlines AA5281
08:41
Cincinnati (CVG)

10:25
Charlotte (CLT)
Effective 2026-05-21 through 2026-07-01
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:44, non-stop
Canadair CRJ 900 (CR9)
Direct Flights:
American Airlines AA5281
08:42
Cincinnati (CVG)

10:25
Charlotte (CLT)
Effective 2026-07-02 through 2026-08-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:43, non-stop
Canadair CRJ 900 (CR9)
Direct Flights:
American Airlines AA5281
08:44
Cincinnati (CVG)

10:25
Charlotte (CLT)
Effective 2026-08-05 through 2026-09-08
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:41, non-stop
Canadair CRJ 900 (CR9)
Direct Flights:
American Airlines AA5281
08:45
Cincinnati (CVG)

10:25
Charlotte (CLT)
Effective 2026-04-07 through 2026-05-20
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:40, non-stop
Canadair CRJ 900 (CR9)
Direct Flights:
American Airlines AA5281
10:20
Ronald Reagan Washington (DCA) 2

12:01
Rochester (ROC)
Effective 2026-02-12 through 2026-03-06
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Duration: 1:41, non-stop
Canadair CRJ 900 (CR9)
Direct Flights:
American Airlines AA5281
12:31
Rochester (ROC)

13:59
Ronald Reagan Washington (DCA) 2
Effective 2026-02-12 through 2026-03-06
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Duration: 1:28, non-stop
Canadair CRJ 900 (CR9)
Direct Flights:
American Airlines AA5281
20:45
Dallas Fort Worth (DFW)

22:53
Moline (MLI)
Effective 2026-03-08 through 2026-04-06
Mon
Tue
-
Wed
Thu
Fri
Sat
Sun
Duration: 2:08, non-stop
Canadair CRJ 900 (CR9)
Direct Flights:
American Airlines AA5281
21:05
Dallas Fort Worth (DFW)

23:13
Moline (MLI)
Effective 2026-03-10 through 2026-03-31
Mon
-
Tue
Wed
-
Thu
-
Fri
-
Sat
-
Sun
-
Duration: 2:08, non-stop
Canadair CRJ 900 (CR9)
Direct Flights:
American Airlines AA5281
23:00
Charlotte (CLT)

23:58
Greenville/Spartanburg (GSP)
Valid until 2026-01-05
Mon
Tue
Wed
-
Thu
Fri
Sat
Sun
Duration: 0:58, non-stop
Canadair CRJ 900 (CR9)
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This flight number is listed as serving the following routes:
  • Charlotte (CLT) - Greenville/Spartanburg (GSP)
  • Chattanooga (CHA) - Dallas Fort Worth (DFW)
  • Cincinnati (CVG) - Charlotte (CLT)
  • Dallas Fort Worth (DFW) - Moline (MLI)
  • Ronald Reagan Washington (DCA) - Rochester (ROC)
All American Airlines flights
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