American Airlines flight AA 4543: Multiple routes

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FLIGHT SCHEDULE
Direct Flights:
Daily 06:00 New York John F. Kennedy (JFK) 8 07:17 Boston Logan (BOS) B
AA 4543 Non-stop Embraer EMB 175 (E75) 1:17 Effective 2026-03-08 through 2026-04-06
Mon,Tue,Fri-Sun 07:00 New York LaGuardia (LGA) B 09:37 Atlanta (ATL) N
AA 4543 Non-stop Embraer EMB 175 (E75) 2:37 Valid until 2026-01-05
Tue 07:02 Albany (ALB) 09:08 Chicago O'Hare (ORD) 3
AA 4543 Non-stop Embraer EMB 175 (E75) 3:06 Operates only on 2026-01-06
Mon-Fri 08:54 Pittsburgh (PIT) 10:30 New York LaGuardia (LGA) B
AA 4543 Non-stop Embraer EMB 170 / EMB 175 (E70) 1:36 Effective 2026-02-12 through 2026-03-06
Daily 10:02 Ronald Reagan Washington (DCA) 2 11:45 Nantucket (ACK)
AA 4543 Non-stop Embraer EMB 175 (E75) 1:43 Effective 2026-06-18 through 2026-07-01
Mon,Tue,Fri,Sun 10:12 Atlanta (ATL) N 12:36 New York LaGuardia (LGA) B
AA 4543 Non-stop Embraer EMB 175 (E75) 2:24 Valid until 2026-01-05
Daily 10:40 Boston Logan (BOS) B 13:09 Traverse City (TVC)
AA 4543 Non-stop Embraer EMB 175 (E75) 2:29 Effective 2026-07-02 through 2026-08-04
Daily 12:15 Nantucket (ACK) 13:59 Ronald Reagan Washington (DCA) 2
AA 4543 Non-stop Embraer EMB 175 (E75) 1:44 Effective 2026-06-18 through 2026-07-01
Daily 13:45 Traverse City (TVC) 15:58 Boston Logan (BOS) B
AA 4543 Non-stop Embraer EMB 175 (E75) 2:13 Effective 2026-07-02 through 2026-08-04
Daily 14:30 New York John F. Kennedy (JFK) 8 16:13 Chicago O'Hare (ORD) 3
AA 4543 Non-stop Embraer EMB 175 (E75) 2:43 Effective from 2026-10-05
Daily 16:16 Chicago O'Hare (ORD) 3 19:19 Atlanta (ATL) N
AA 4543 Non-stop Embraer EMB 175 (E75) 2:03 Effective 2026-08-05 through 2026-09-08
Daily 18:45 New York LaGuardia (LGA) B 21:15 Atlanta (ATL) N
AA 4543 Non-stop Embraer EMB 175 (E75) 2:30 Effective 2026-09-09 through 2026-10-04
Daily 19:49 Atlanta (ATL) N 21:14 Chicago O'Hare (ORD) 3
AA 4543 Non-stop Embraer EMB 175 (E75) 2:25 Effective 2026-08-05 through 2026-09-08
Daily 21:00 Philadelphia (PHL) 23:05 Indianapolis (IND)
AA 4543 Non-stop Embraer EMB 175 (E75) 2:05 Effective 2026-04-07 through 2026-05-20
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This flight number is listed as serving the following routes:


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American Airlines flight AA 4543: Multiple routes
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Select flight date:
FLIGHT SCHEDULE
Direct Flights:
American Airlines AA4543
06:00
New York John F. Kennedy (JFK) 8

07:17
Boston Logan (BOS) B
Effective 2026-03-08 through 2026-04-06
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:17, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4543
07:00
New York LaGuardia (LGA) B

09:37
Atlanta (ATL) N
Valid until 2026-01-05
Mon
Tue
Wed
-
Thu
-
Fri
Sat
Sun
Duration: 2:37, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4543
07:02
Albany (ALB)

09:08
Chicago O'Hare (ORD) 3
Operates only on 2026-01-06
Mon
-
Tue
Wed
-
Thu
-
Fri
-
Sat
-
Sun
-
Duration: 3:06, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4543
08:54
Pittsburgh (PIT)

10:30
New York LaGuardia (LGA) B
Effective 2026-02-12 through 2026-03-06
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
-
Duration: 1:36, non-stop
Embraer EMB 170 / EMB 175 (E70)
Direct Flights:
American Airlines AA4543
10:02
Ronald Reagan Washington (DCA) 2

11:45
Nantucket (ACK)
Effective 2026-06-18 through 2026-07-01
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:43, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4543
10:12
Atlanta (ATL) N

12:36
New York LaGuardia (LGA) B
Valid until 2026-01-05
Mon
Tue
Wed
-
Thu
-
Fri
Sat
-
Sun
Duration: 2:24, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4543
10:40
Boston Logan (BOS) B

13:09
Traverse City (TVC)
Effective 2026-07-02 through 2026-08-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:29, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4543
12:15
Nantucket (ACK)

13:59
Ronald Reagan Washington (DCA) 2
Effective 2026-06-18 through 2026-07-01
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:44, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4543
13:45
Traverse City (TVC)

15:58
Boston Logan (BOS) B
Effective 2026-07-02 through 2026-08-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:13, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4543
14:30
New York John F. Kennedy (JFK) 8

16:13
Chicago O'Hare (ORD) 3
Effective from 2026-10-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:43, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4543
16:16
Chicago O'Hare (ORD) 3

19:19
Atlanta (ATL) N
Effective 2026-08-05 through 2026-09-08
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:03, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4543
18:45
New York LaGuardia (LGA) B

21:15
Atlanta (ATL) N
Effective 2026-09-09 through 2026-10-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:30, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4543
19:49
Atlanta (ATL) N

21:14
Chicago O'Hare (ORD) 3
Effective 2026-08-05 through 2026-09-08
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:25, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4543
21:00
Philadelphia (PHL)

23:05
Indianapolis (IND)
Effective 2026-04-07 through 2026-05-20
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:05, non-stop
Embraer EMB 175 (E75)
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This flight number is listed as serving the following routes:
  • Albany (ALB) - Chicago O'Hare (ORD)
  • Atlanta (ATL) - New York LaGuardia (LGA)
  • Boston Logan (BOS) - Traverse City (TVC)
  • Chicago O'Hare (ORD) - Atlanta (ATL)
  • New York John F. Kennedy (JFK) - Boston Logan (BOS)
  • New York John F. Kennedy (JFK) - Chicago O'Hare (ORD)
  • Philadelphia (PHL) - Indianapolis (IND)
  • Pittsburgh (PIT) - New York LaGuardia (LGA)
  • Ronald Reagan Washington (DCA) - Nantucket (ACK)
All American Airlines flights
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