American Airlines flight AA 4459: Multiple routes

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Select flight date:
FLIGHT SCHEDULE
Direct Flights:
Sat 07:45 New York LaGuardia (LGA) B 09:34 Raleigh/Durham (RDU) 2
AA 4459 Non-stop Embraer EMB 175 (E75) 1:49 Effective 2026-03-14 through 2026-04-04
Mon-Fri 08:09 New York LaGuardia (LGA) B 10:03 Raleigh/Durham (RDU) 2
AA 4459 Non-stop Embraer EMB 175 (E75) 1:54 Effective 2026-02-12 through 2026-03-06
Mon-Fri 08:10 New York LaGuardia (LGA) B 09:59 Raleigh/Durham (RDU) 2
AA 4459 Non-stop Embraer EMB 175 (E75) 1:49 Effective 2026-03-09 through 2026-04-06
Daily 08:10 Philadelphia (PHL) 10:10 Indianapolis (IND)
AA 4459 Non-stop Embraer EMB 175 (E75) 2:00 Effective 2026-07-02 through 2026-08-04
Mon-Wed,Fri,Sun 08:45 New York LaGuardia (LGA) B 10:32 Raleigh/Durham (RDU) 2
AA 4459 Non-stop Embraer EMB 175 (E75) 1:47 Valid until 2026-01-05
Sat 09:30 Raleigh/Durham (RDU) 2 11:11 New York LaGuardia (LGA) B
AA 4459 Non-stop Embraer EMB 175 (E75) 1:41 Valid until 2026-01-03
Sat 10:05 Raleigh/Durham (RDU) 2 11:47 New York LaGuardia (LGA) B
AA 4459 Non-stop Embraer EMB 175 (E75) 1:42 Effective 2026-02-14 through 2026-03-07
Sat 10:06 Raleigh/Durham (RDU) 2 11:47 New York LaGuardia (LGA) B
AA 4459 Non-stop Embraer EMB 175 (E75) 1:41 Effective 2026-03-14 through 2026-04-04
Daily 10:13 New York LaGuardia (LGA) B 12:00 Raleigh/Durham (RDU) 2
AA 4459 Non-stop Embraer EMB 175 (E75) 1:47 Effective 2026-08-05 through 2026-09-08
Sun 10:30 Raleigh/Durham (RDU) 2 12:12 New York LaGuardia (LGA) B
AA 4459 Non-stop Embraer EMB 175 (E75) 1:42 Effective 2026-02-15 through 2026-03-01
Daily 10:30 New York LaGuardia (LGA) B 12:16 Raleigh/Durham (RDU) 2
AA 4459 Non-stop Embraer EMB 175 (E75) 1:46 Effective from 2026-10-05
Sun 10:31 Raleigh/Durham (RDU) 2 12:12 New York LaGuardia (LGA) B
AA 4459 Non-stop Embraer EMB 175 (E75) 1:41 Effective 2026-03-08 through 2026-04-05
Fri 10:33 Raleigh/Durham (RDU) 2 12:15 New York LaGuardia (LGA) B
AA 4459 Non-stop Embraer EMB 175 (E75) 1:42 Operates only on 2026-02-13
Mon-Fri 10:35 Raleigh/Durham (RDU) 2 12:16 New York LaGuardia (LGA) B
AA 4459 Non-stop Embraer EMB 175 (E75) 1:41 Effective 2026-03-09 through 2026-04-06
Daily 11:02 Indianapolis (IND) 12:55 Philadelphia (PHL)
AA 4459 Non-stop Embraer EMB 175 (E75) 1:53 Effective 2026-07-02 through 2026-08-04
Wed,Thu 11:10 Raleigh/Durham (RDU) 2 12:51 New York LaGuardia (LGA) B
AA 4459 Non-stop Embraer EMB 175 (E75) 1:41 Valid until 2026-01-01
Mon,Tue,Fri,Sun 11:13 Raleigh/Durham (RDU) 2 12:54 New York LaGuardia (LGA) B
AA 4459 Non-stop Embraer EMB 175 (E75) 1:41 Valid until 2026-01-05
Daily 11:59 Raleigh/Durham (RDU) 2 13:35 New York LaGuardia (LGA) B
AA 4459 Non-stop Embraer EMB 175 (E75) 1:36 Effective 2026-09-09 through 2026-10-04
Daily 12:30 Raleigh/Durham (RDU) 2 14:12 New York LaGuardia (LGA) B
AA 4459 Non-stop Embraer EMB 175 (E75) 1:42 Effective 2026-08-05 through 2026-09-08
Daily 12:47 Raleigh/Durham (RDU) 2 14:29 New York LaGuardia (LGA) B
AA 4459 Non-stop Embraer EMB 175 (E75) 1:42 Effective from 2026-10-05
Daily 13:44 Ronald Reagan Washington (DCA) 2 15:04 Memphis (MEM)
AA 4459 Non-stop Embraer EMB 175 (E75) 2:20 Effective 2026-05-21 through 2026-07-01
Sat 17:02 Raleigh/Durham (RDU) 2 18:44 New York LaGuardia (LGA) B
AA 4459 Non-stop Embraer EMB 170 / EMB 175 (E70) 1:42 Effective 2026-01-10 through 2026-02-07
Mon,Thu,Fri,Sun 17:17 Raleigh/Durham (RDU) 2 18:59 New York LaGuardia (LGA) B
AA 4459 Non-stop Embraer EMB 175 (E75) 1:42 Effective 2026-01-08 through 2026-02-09
Daily 17:25 Indianapolis (IND) 19:26 New York LaGuardia (LGA) B
AA 4459 Non-stop Embraer EMB 175 (E75) 2:01 Effective 2026-04-07 through 2026-05-20
Daily 18:16 Memphis (MEM) 21:30 Ronald Reagan Washington (DCA) 2
AA 4459 Non-stop Embraer EMB 175 (E75) 2:14 Effective 2026-05-21 through 2026-07-01
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This flight number is listed as serving the following routes:


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American Airlines flight AA 4459: Multiple routes
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Select flight date:
FLIGHT SCHEDULE
Direct Flights:
American Airlines AA4459
07:45
New York LaGuardia (LGA) B

09:34
Raleigh/Durham (RDU) 2
Effective 2026-03-14 through 2026-04-04
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Duration: 1:49, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4459
08:09
New York LaGuardia (LGA) B

10:03
Raleigh/Durham (RDU) 2
Effective 2026-02-12 through 2026-03-06
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
-
Duration: 1:54, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4459
08:10
New York LaGuardia (LGA) B

09:59
Raleigh/Durham (RDU) 2
Effective 2026-03-09 through 2026-04-06
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
-
Duration: 1:49, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4459
08:10
Philadelphia (PHL)

10:10
Indianapolis (IND)
Effective 2026-07-02 through 2026-08-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:00, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4459
08:45
New York LaGuardia (LGA) B

10:32
Raleigh/Durham (RDU) 2
Valid until 2026-01-05
Mon
Tue
Wed
Thu
-
Fri
Sat
-
Sun
Duration: 1:47, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4459
09:30
Raleigh/Durham (RDU) 2

11:11
New York LaGuardia (LGA) B
Valid until 2026-01-03
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Duration: 1:41, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4459
10:05
Raleigh/Durham (RDU) 2

11:47
New York LaGuardia (LGA) B
Effective 2026-02-14 through 2026-03-07
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Duration: 1:42, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4459
10:06
Raleigh/Durham (RDU) 2

11:47
New York LaGuardia (LGA) B
Effective 2026-03-14 through 2026-04-04
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Duration: 1:41, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4459
10:13
New York LaGuardia (LGA) B

12:00
Raleigh/Durham (RDU) 2
Effective 2026-08-05 through 2026-09-08
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:47, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4459
10:30
Raleigh/Durham (RDU) 2

12:12
New York LaGuardia (LGA) B
Effective 2026-02-15 through 2026-03-01
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
-
Sun
Duration: 1:42, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4459
10:30
New York LaGuardia (LGA) B

12:16
Raleigh/Durham (RDU) 2
Effective from 2026-10-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:46, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4459
10:31
Raleigh/Durham (RDU) 2

12:12
New York LaGuardia (LGA) B
Effective 2026-03-08 through 2026-04-05
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
-
Sun
Duration: 1:41, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4459
10:33
Raleigh/Durham (RDU) 2

12:15
New York LaGuardia (LGA) B
Operates only on 2026-02-13
Mon
-
Tue
-
Wed
-
Thu
-
Fri
Sat
-
Sun
-
Duration: 1:42, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4459
10:35
Raleigh/Durham (RDU) 2

12:16
New York LaGuardia (LGA) B
Effective 2026-03-09 through 2026-04-06
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
-
Duration: 1:41, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4459
11:02
Indianapolis (IND)

12:55
Philadelphia (PHL)
Effective 2026-07-02 through 2026-08-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:53, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4459
11:10
Raleigh/Durham (RDU) 2

12:51
New York LaGuardia (LGA) B
Valid until 2026-01-01
Mon
-
Tue
-
Wed
Thu
Fri
-
Sat
-
Sun
-
Duration: 1:41, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4459
11:13
Raleigh/Durham (RDU) 2

12:54
New York LaGuardia (LGA) B
Valid until 2026-01-05
Mon
Tue
Wed
-
Thu
-
Fri
Sat
-
Sun
Duration: 1:41, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4459
11:59
Raleigh/Durham (RDU) 2

13:35
New York LaGuardia (LGA) B
Effective 2026-09-09 through 2026-10-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:36, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4459
12:30
Raleigh/Durham (RDU) 2

14:12
New York LaGuardia (LGA) B
Effective 2026-08-05 through 2026-09-08
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:42, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4459
12:47
Raleigh/Durham (RDU) 2

14:29
New York LaGuardia (LGA) B
Effective from 2026-10-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:42, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4459
13:44
Ronald Reagan Washington (DCA) 2

15:04
Memphis (MEM)
Effective 2026-05-21 through 2026-07-01
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:20, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4459
17:02
Raleigh/Durham (RDU) 2

18:44
New York LaGuardia (LGA) B
Effective 2026-01-10 through 2026-02-07
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Duration: 1:42, non-stop
Embraer EMB 170 / EMB 175 (E70)
Direct Flights:
American Airlines AA4459
17:17
Raleigh/Durham (RDU) 2

18:59
New York LaGuardia (LGA) B
Effective 2026-01-08 through 2026-02-09
Mon
Tue
-
Wed
-
Thu
Fri
Sat
-
Sun
Duration: 1:42, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4459
17:25
Indianapolis (IND)

19:26
New York LaGuardia (LGA) B
Effective 2026-04-07 through 2026-05-20
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:01, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4459
18:16
Memphis (MEM)

21:30
Ronald Reagan Washington (DCA) 2
Effective 2026-05-21 through 2026-07-01
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:14, non-stop
Embraer EMB 175 (E75)
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This flight number is listed as serving the following routes:
  • Indianapolis (IND) - New York LaGuardia (LGA)
  • New York LaGuardia (LGA) - Raleigh/Durham (RDU)
  • Philadelphia (PHL) - Indianapolis (IND)
  • Ronald Reagan Washington (DCA) - Memphis (MEM)
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