American Airlines flight AA 4390: Multiple routes

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FLIGHT SCHEDULE
Direct Flights:
Daily 05:00 Des Moines (DSM) 06:10 Chicago O'Hare (ORD) 3
AA 4390 Non-stop Embraer EMB 175 (E75) 1:10 Effective 2026-09-09 through 2026-10-04
Thu 07:21 Ronald Reagan Washington (DCA) 2 09:39 New Orleans (MSY)
AA 4390 Non-stop Embraer EMB 175 (E75) 3:18 Operates only on 2026-02-12
Mon,Tue,Thu,Fri 07:35 Ronald Reagan Washington (DCA) 2 09:53 New Orleans (MSY)
AA 4390 Non-stop Embraer EMB 175 (E75) 3:18 Effective 2026-02-13 through 2026-02-24
Mon-Fri 07:35 Ronald Reagan Washington (DCA) 2 09:53 New Orleans (MSY)
AA 4390 Non-stop Embraer EMB 175 (E75) 3:18 Effective 2026-02-25 through 2026-03-06
Mon-Fri 07:41 Ronald Reagan Washington (DCA) 2 09:52 New Orleans (MSY)
AA 4390 Non-stop Embraer EMB 175 (E75) 3:11 Effective 2026-03-09 through 2026-04-06
Daily 07:59 New York John F. Kennedy (JFK) 8 09:55 Raleigh/Durham (RDU) 2
AA 4390 Non-stop Embraer EMB 175 (E75) 1:56 Effective 2026-01-06 through 2026-02-11
Daily 08:04 New York LaGuardia (LGA) B 10:13 Greenville/Spartanburg (GSP)
AA 4390 Non-stop Embraer EMB 170 / EMB 175 (E70) 2:09 Effective 2026-08-05 through 2026-09-08
Sat 08:12 Ronald Reagan Washington (DCA) 2 10:30 New Orleans (MSY)
AA 4390 Non-stop Embraer EMB 175 (E75) 3:18 Effective 2026-02-14 through 2026-03-07
Thu 10:09 New Orleans (MSY) 13:44 Ronald Reagan Washington (DCA) 2
AA 4390 Non-stop Embraer EMB 175 (E75) 2:35 Operates only on 2026-02-12
Mon-Fri 10:22 New Orleans (MSY) 13:59 Ronald Reagan Washington (DCA) 2
AA 4390 Non-stop Embraer EMB 175 (E75) 2:37 Effective 2026-03-09 through 2026-04-06
Mon,Tue,Thu,Fri 10:23 New Orleans (MSY) 13:59 Ronald Reagan Washington (DCA) 2
AA 4390 Non-stop Embraer EMB 175 (E75) 2:36 Effective 2026-02-13 through 2026-02-24
Mon-Fri 10:23 New Orleans (MSY) 13:59 Ronald Reagan Washington (DCA) 2
AA 4390 Non-stop Embraer EMB 175 (E75) 2:36 Effective 2026-02-25 through 2026-03-06
Daily 10:43 Greenville/Spartanburg (GSP) 12:40 New York LaGuardia (LGA) B
AA 4390 Non-stop Embraer EMB 170 / EMB 175 (E70) 1:57 Effective 2026-08-05 through 2026-09-08
Daily 10:53 Chicago O'Hare (ORD) 3 13:30 Louisville (SDF)
AA 4390 Non-stop Embraer EMB 175 (E75) 1:37 Valid until 2026-01-05
Sat 11:00 New Orleans (MSY) 14:37 Ronald Reagan Washington (DCA) 2
AA 4390 Non-stop Embraer EMB 175 (E75) 2:37 Effective 2026-02-14 through 2026-03-07
Daily 13:35 Philadelphia (PHL) 15:02 Burlington (BTV)
AA 4390 Non-stop Embraer EMB 175 (E75) 1:27 Effective 2026-07-02 through 2026-08-04
Daily 14:00 Louisville (SDF) 14:45 Chicago O'Hare (ORD) 3
AA 4390 Non-stop Embraer EMB 175 (E75) 1:45 Valid until 2026-01-05
Daily 15:35 Philadelphia (PHL) 17:08 Cleveland (CLE)
AA 4390 Non-stop Embraer EMB 175 (E75) 1:33 Effective 2026-05-21 through 2026-07-01
Daily 15:40 New York LaGuardia (LGA) B 17:29 Cleveland (CLE)
AA 4390 Non-stop Embraer EMB 170 / EMB 175 (E70) 1:49 Effective 2026-04-07 through 2026-05-20
Daily 15:58 New York LaGuardia (LGA) B 17:30 Norfolk (ORF)
AA 4390 Non-stop Embraer EMB 170 / EMB 175 (E70) 1:32 Effective from 2026-10-05
Daily 16:24 Burlington (BTV) 17:55 Philadelphia (PHL)
AA 4390 Non-stop Embraer EMB 175 (E75) 1:31 Effective 2026-07-02 through 2026-08-04
Daily 17:59 Cleveland (CLE) 19:36 New York LaGuardia (LGA) B
AA 4390 Non-stop Embraer EMB 170 / EMB 175 (E70) 1:37 Effective 2026-04-07 through 2026-05-20
Daily 18:00 Norfolk (ORF) 19:28 New York LaGuardia (LGA) B
AA 4390 Non-stop Embraer EMB 170 / EMB 175 (E70) 1:28 Effective from 2026-10-05
Daily 18:50 Cleveland (CLE) 20:25 Philadelphia (PHL)
AA 4390 Non-stop Embraer EMB 175 (E75) 1:35 Effective 2026-05-21 through 2026-07-01
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This flight number is listed as serving the following routes:
American Airlines flight AA 4390: Multiple routes
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Select flight date:
FLIGHT SCHEDULE
Direct Flights:

American Airlines AA4390
Effective 2026-09-09 through 2026-10-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:10, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4390
Operates only on 2026-02-12
Mon
-
Tue
-
Wed
-
Thu
Fri
-
Sat
-
Sun
-
Duration: 3:18, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4390
Effective 2026-02-13 through 2026-02-24
Mon
Tue
Wed
-
Thu
Fri
Sat
-
Sun
-
Duration: 3:18, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4390
Effective 2026-02-25 through 2026-03-06
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
-
Duration: 3:18, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4390
Effective 2026-03-09 through 2026-04-06
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
-
Duration: 3:11, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4390
Effective 2026-01-06 through 2026-02-11
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:56, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4390
Effective 2026-08-05 through 2026-09-08
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:09, non-stop
Embraer EMB 170 / EMB 175 (E70)

Direct Flights:

American Airlines AA4390
Effective 2026-02-14 through 2026-03-07
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Duration: 3:18, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4390
Operates only on 2026-02-12
Mon
-
Tue
-
Wed
-
Thu
Fri
-
Sat
-
Sun
-
Duration: 2:35, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4390
Effective 2026-03-09 through 2026-04-06
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
-
Duration: 2:37, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4390
Effective 2026-02-13 through 2026-02-24
Mon
Tue
Wed
-
Thu
Fri
Sat
-
Sun
-
Duration: 2:36, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4390
Effective 2026-02-25 through 2026-03-06
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
-
Duration: 2:36, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4390
Effective 2026-08-05 through 2026-09-08
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:57, non-stop
Embraer EMB 170 / EMB 175 (E70)

Direct Flights:

American Airlines AA4390
Valid until 2026-01-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:37, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4390
Effective 2026-02-14 through 2026-03-07
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Duration: 2:37, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4390
Effective 2026-07-02 through 2026-08-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:27, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4390
Valid until 2026-01-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:45, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4390
Effective 2026-05-21 through 2026-07-01
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:33, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4390
Effective 2026-04-07 through 2026-05-20
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:49, non-stop
Embraer EMB 170 / EMB 175 (E70)

Direct Flights:

American Airlines AA4390
Effective from 2026-10-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:32, non-stop
Embraer EMB 170 / EMB 175 (E70)

Direct Flights:

American Airlines AA4390
Effective 2026-07-02 through 2026-08-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:31, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4390
Effective 2026-04-07 through 2026-05-20
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:37, non-stop
Embraer EMB 170 / EMB 175 (E70)

Direct Flights:

American Airlines AA4390
Effective from 2026-10-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:28, non-stop
Embraer EMB 170 / EMB 175 (E70)

Direct Flights:

American Airlines AA4390
Effective 2026-05-21 through 2026-07-01
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:35, non-stop
Embraer EMB 175 (E75)
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This flight number is listed as serving the following routes:
  • Chicago O'Hare (ORD) - Louisville (SDF)
  • Cleveland (CLE) - New York LaGuardia (LGA)
  • Cleveland (CLE) - Philadelphia (PHL)
  • Des Moines (DSM) - Chicago O'Hare (ORD)
  • New York John F. Kennedy (JFK) - Raleigh/Durham (RDU)
  • New York LaGuardia (LGA) - Greenville/Spartanburg (GSP)
  • New York LaGuardia (LGA) - Norfolk (ORF)
  • Philadelphia (PHL) - Burlington (BTV)
  • Ronald Reagan Washington (DCA) - New Orleans (MSY)